On the mathematical model with morphological change of tumorigenesis in view

Ouchi, Noriyuki

Hoken Butsuri, 40(2), p.166 - 169, 2005/06

https://doi.org/10.5453/jhps.40.166

Development of the new mathematical model of the carcinogenesis in a low dose in mind is reported. The new model which describes from cell canceration to the tumorigenesis in consideration of the physical dynamics of a cell level was built. In a cell group level, it has both intra-cellular dynamics, such as mutation, cell division, and cell death, and physical dynamics such as, adhesion between cells, modification, and movement, and a model can investigate with time that tumor is formed.